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Quality Assurance & Testing

Mageck

Mageck processes pooled CRISPR screen FASTQ reads and guide‑count matrices to validate guide libraries and assess replicate and library quality control. It generates gene hit rankings with effect sizes and false discovery rates for knockout, CRISPRi, and CRISPRa screens, supporting both enrichment and depletion analyses. Researchers and bioinformaticians use Mageck to run MAGeCK count and test workflows and to retrieve public dependency‑score data from DepMap.

Publisher / source
Scientific Agent Skills
Upstream record
K-Dense-AI/scientific-agent-skills
Version
Version 2
Published
Publication review
Approved for publication · recorded passed scan 2026-10-01
Content fingerprint
562d7e2cb2febef14ab722bc29cd33983b523da287fb02b64eadf18702d4a9d1