AI & Machine Learning

AlterLab Chai

Predict biomolecular complexes with Chai-1, an open AlphaFold3-style model that folds multi-entity assemblies (proteins, ligands, nucleic acids) from a single typed FASTA — strong on antibody–antigen and protein–ligand complexes, with optional MSA and restraint inputs. Use when predicting an antibody–antigen complex, folding a mixed protein/ligand/nucleic-acid assembly described in one FASTA, or generating a complex with experimental restraints. For binding-affinity prediction or a ligand-focused co-fold prefer alterlab-boltz; for protein-only or protein–protein folding prefer alterlab-alphafold; to dock into a fixed receptor prefer alterlab-diffdock. Part of the AlterLab Academic Skills suite.

Publisher / source
AlterLab-IEU/AlterLab-Academic-Skills (found on the CSV list)
Upstream record
AlterLab-IEU/AlterLab-Academic-Skills
Version
Version 2
Published
Publication review
Approved for publication
Content fingerprint
9795eef161c652b7723020296cdca749be098bed6d2eee7c34329d1b7308b488