Medical & Healthcare
Cross-ancestry / cross-biobank phenome-wide association (PheWAS) and replication. Given ONE variant (rsID) or ONE gene, look up every phenotype it associates with across European/UK (UKB-TOPMed), Finnish (FinnGen), Japanese (BioBank Japan), and Taiwanese (TPMI) biobanks, plus exome-wide gene-burden PheWAS (Genebass), then judge whether an association replicates across ancestries or is population-specific. Use whenever the user asks "what else is this variant/gene associated with", "does this association replicate in other ancestries / biobanks", "is this effect East-Asian-specific", "pleiotropy of rsXXX", "phenome scan", or wants to compare effect sizes/allele frequencies of a variant across populations. NOT for the forward direction (trait → which SNPs: use the gwas-* skills), NOT for fine-mapping a locus (use tooluniverse-gwas-finemapping), and NOT for single-SNP mechanism tracing in one population (use tooluniverse-gwas-snp-interpretation).
Publisher / source
mims-harvard/ToolUniverse (found on GitHub top repositories)
Upstream record
Version
Version 1
Published
2026-11-10
Publication review
Approved for publication · recorded passed scan 2026-11-10
Content fingerprint
55b8479835f8b7a7eeff08a898440006d3f9d95d404137ce8a0c4fc9f0a45afc
Review before you use it
Publication approval is a recorded review state, not a guarantee of safe execution. Check the upstream license, required tools and permissions, and test in your intended client.
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Source: https://prompeteer.ai/skills-hub/8487d0eb-f28e-455b-ab09-5c6be55e99a8